Cerca:the ant

Neurotwin is a Trilogy:

Part I
In the fight against Alzheimer's, epilepsy, schizophrenia and other diseases characterized by an imbalance in neuronal activity, there are chemical weapons, such as those that try to prevent the protein fragments known as beta-amyloid plaques from developing in the cerebral cortex , and physical, such as electrical stimulation that allow to restore the functionality of brain cells. This last resort, which has already been shown to be effective in modifying the activity of the cerebral cortex, is today a weapon of general intervention. Converting it to precision requires the development of individualized and predictive brain models that allow identifying where and how much to stimulate each patient. To achieve this, an international European team is working on the creation of virtual replicas of the most unknown organ in the body: the Neurotwin project.

According to recent research, the decrease in power in the neuronal oscillations of the gamma band of the cerebral cortex (a pattern whose frequency ranges between 20 and 50 Hertz) favors the development of protein fragments related to Alzheimer's.

Transcranial application of weak electrical currents has proven to be an effective and painless way to modulate brain activity without side effects.

The objective is to create complete computational models of the brain with real data of living beings (human patients) and that allow to anticipate and specify the effects of non-invasive stimulation techniques on neurological mechanisms.

"Never turn your back on a friend."
- Alfred Hitchcock

Part II
The Neurotwin project is the successor to an initiative that encompasses many projects called Virtual Physiological Human, which was based on the idea of creating a complete model of a human being on a computer, to perform non-invasive tests at the computational level. Now the concept has been derived to "Digital Twin", which seeks not only to have an equal computational model for everyone, but to create "twin" digital models of each patient in order to be able to make personalized medicine from the genome of each individual. Specifically, in our project, we have focused on digital twin brains, which would be representations of patient brains created from data extracted with current neuroimaging and brain activity monitoring techniques.

"Mirrors are used to see the face, Art to see the soul."
- George Bernard Shaw

Part III
A digital twin is a computer system programmed in such a way that, receiving the same inputs as the physical object or process it is a twin of, it provides the same outputs.

Characteristics of digital twin technology
1 Connectivity
2 Homogenization
3 Reprogrammable and intelligent
4 Digital traces

"There is no light without shadows and no fullness of mind without imperfections. Life requires for its realization, not perfection, but fullness. Without imperfection, there is no progress or growth."
- Carl Gustav Young

Stephen Steinbrink discovered a short YouTube video of a street magician who approaches a highschooler walking home in Barstow, California. “Here, let me show you my idea,” he says, as he places a quarter on the kid’s hand. The magician performs some relaxed flourishes, and the coin vanishes. In silence, the kid stares at his hand at the nothing where there once, indisputably, was something, until his wonder finds a single word: “Cool.” The title of Disappearing Coin, the new album from Oakland songwriter Stephen Steinbrink, comes from this short clip. “When I look at it now,” he says, “I relate to the kid, who’s obviously uneasy in his body, and going through the experience of being a teenager in the early 2000s growing up in a bleak desert town like I did. I also relate to the coin, an inanimate disc of possibility. And I relate to the magician, an absurd facilitator of sending what is tactile and concrete into the wispy conceptual realm.” “I’ve watched it probably a hundred times,” he says. “It cracked me up but also blew my mind open the feeling of wonder I experienced watching this video became a guide as I navigated new ways of staying in the realm of what’s both real and magical.” Following the 2018 release of Utopia Teased, Steinbrink completed an apprenticeship in the nearly-lost art of Stained Glass, becoming a glazier at a studio that over three years, fully restored the enormous 90-year-old windows in San Francisco’s Grace Cathedral. He committed to his Buddhist study, beginning lay monastic training before the process was thwarted by the pandemic. He dove deeper into music production for other artists, engineering two albums by Boy Scouts released on Anti- Records in 2018 and 2021. Steinbrink delighted in the way these pursuits pulled at the thread of ego’s tapestry and decentralized him from his craft, allowing him to embody a new role as a creative caretaker engaging in practices that felt communal and restorative. “As I slowly began writing for myself again, I tried to imbue my new songs with this sense of playfulness and wonder I felt while exploring these other interests.” He says. Feeling unlocked from the pressures of perfection that he often felt in his earlier work, creating Disappearing Coin felt buoyant and healing. “The album feels like an integration of all of my past musical selves zeroing in on the present,” Steinbrink explains, “I felt free to explore new ways of writing, through different perspectives, experimenting with fictional songwriting, visual archetypal language, and total collaboration.” This “total collaboration” was a joyous new venture after years of solo performing and recording. The album can be seen as a 42 minute session of show and tell, the manifestation of Steinbrink repeating the mantra of “Here, let me show you my idea” to himself over and over. Disappearing Coin is at once a welcome return for the veteran Steinbrink and the debut of a totally new artist, one who has found a new path to himself with new goals of openness, curiosity, and self-acceptance. “Recalls the magic pop purity of Arthur Russell...its minimalism manages to feel enlightened and transformative.” PITCHFORK // “Melodic and self-assured. Steinbrink delivers his knotted lyricism with a smooth lilt.

Fiddlehead's third album Death is Nothing to Us is a defiant, new chapter for the band. Since 2014, the Boston-based group have been honing their unique sound, bringing together the energy of hardcore, the anthemic melodies of `90s alternative, and the unbridled passion of Revolution Summer era emo. Their previous albums, 2018's Springtime and Blind and 2021's Between The Richness, dealt heavily with grief from different perspectives, and now their latest feels like a de facto culmination, drawing together many of the catalog's through-lines sonically and lyrically. The band again teamed with producer Chris Teti for their third record, and his punchy production captures Fiddlehead's live energy while showcasing the massive guitars and undeniable catchiness that makes their music so immensely satisfying. The album's concise 27 minutes sound like a natural extension of all of the band's strengths, but is glued together by vocalist Pat Flynn's singular tuneful roar. Flynn, since his time as the vocalist of Have Heart and now as Fiddlehead's frontman, has earned a reputation as one of hardcore's most thoughtful lyricists. He interweaves his ruminations on life, death, and all the joy and tragedy in between with references to Roman philosopher Lucretius; the author Jean Améry; other musicians like Bad Brains, Alex G, or Wire, and even references to the band's own back catalog. The humanity across Death Is Nothing To Us is palpable in every note. It's the kind of art that observes pain with real honesty rather than prescribing a solution for it-and in doing so, inadvertently offers some sense of hopefulness. The album finds Fiddlehead so deeply delving into the pain, confusion, nuances, and contradictions of sadness-so willingly wrapping their arms around a concept as existentially baffling as death itself-that they've created an album that is truly life-affirming. Death is Nothing to Us exemplifies so much of what makes Fiddlehead a special band: taking these heady, unanswerable questions and wrestling with them in a very earthbound way, all wrapped up in the urgent power of a three minute punk song.

Sophisticated, suave, and masterfully composed, this 45 is a sonic love letter to late 60s and early 70s soul, nodding to the giants of the genre and bowing to its unsung heroes. With inspiration from artists like The Moments, Baby Huey, The Delfonics, and especially the late Curtis Mayfield, this 7" is drenched in the era-defining tone that can only come from its origins on analog tape. From the first notes of the first track "Beck & Call", the songs shimmer and glow from one moment to the next like a summer's drive with the windows down, with a steady cruise anthem like "Daydreaming" floating by like a cool breeze. Friends since childhood, The Sextones are Mark Sexton (guitar, vocals), Alexander Korostinsky (bass), Daniel Weiss (drums), and Christopher Sexton (piano). Having known each other for so long, their musical chemistry is effortless and forms the foundation of the band's longevity and creative workflow. Despite their bond, each member has been able to channel their creativity into other acclaimed groups_Alexander and Mark with their cinematic-soul project Whatitdo Archive Group, whose acclaimed debut LP The Black Stone Affair was released on Record Kicks in 2021, and Daniel with the soul/jazz group Delvon Lamarr Organ Trio (Colemine Records). Flexing their creative muscle individually has only strengthened The Sextones' collective songwriting ability and heralds their formidable return to the spotlight. With their recent signing to Record Kicks, the self-made heroes of soul begin a new chapter in their sonic journey, ready to scale new heights and plumb deep emotional depths in service of the genre they love.

Audiences who were lucky enough to have seen the film during its special theatrical sneak preview have already discovered that this highly anticipated sequel is nothing short of epic - and much of that is due to the gorgeous, sweeping score by Nathan Johnson. Johnson keeps intact the delicate balance that made KNIVES OUT such a clever score, never undermining the danger that is around every corner, but also brings an intoxicating romanticism to every gorgeous landscape. It’s playful, and sinister all at once.
“I’m thrilled to announce the release of my score for Glass Onion on vinyl, but more specifically, I’m over the moon to be able to join forces again with the wonderful folks at Mondo,” says Johnson. “Everything they do is one-of-a-kind, but with this release they’ve gone above and beyond. We’ve mastered this version specifically for vinyl so that it retains all the orchestral dynamics I’ve written into the score, and I can’t wait for people to get their hands on the artwork and peel back all of the beautiful layers. I know we live in a world of digital ephemera, but I’ll say it again and again: thank God for Mondo.”

J Hus is back with his highly anticipated third album ‘Beautiful And Brutal Yard’, preceded by the raucous street track ‘It’s Crazy’ which charted Top 15 and ‘Who Told You’ (featuring Drake) which debuted at #2 with the 3rd highest UK week 1 singles sales of the year and Hus’ highest single chart to date.

‘B.A.B.Y.’ is the follow-up to his chart-topping album ‘Big Conspiracy’ which earned him the Best Male Award at the Brits and his Top 10 platinum debut ‘Common Sense’ which won an NME award and was nominated for the Mercury Music Prize and Best Album at the Brits.

Fans have come to expect a range of influences and musical styles from Hus’ albums and they will not be disappointed. Across ‘B.A.B.Y’ Hus incorporates elements of afrobeats, drill, R&B and bashment, all delivered in his inimitable lyrical style. The album includes features from Drake, Burna Boy, Jorja Smith, Popcaan and Naira Marley as well as from UK up and comers CB, Villz and Boss Belly.

Having not played his own live shows since 2017 J Hus is announcing a UK Arena tour on Thursday 29th June.

Long Island Sound follow up their acclaimed debut album and accompanying remix EP with Don’t Let Me / Air a limited white label release featuring 2 brand new dancefloor-certified anthems that signal a new era for the duo in both style and effect, while certifying them as masters of their house domain.

The Dublin-based duo of Rob Roche and Tim Nolan have made impressive strides as Long Island Sound for close to a decade now, honing their swooning dance craft via beloved EPs on their Signs Of Space imprint while becoming mainstays of their island’s club and festival circuit thanks to multiple acclaimed DJ sets.

Last year, they reached an impressive feat that few Irish dance acts have before them by releasing their debut album Lost Connection.

A 7-track opus that fused dynamic electronic sounds with contemporary styles of house, techno, and breaks, it signalled an exhilarating new direction for the duo that showcased their exceptional artistry in melody and production and subsequently earned them great acclaim.

An accompanying 5 track remix EP followed this year, featuring quality club reworks of various album cuts from producers Cromby, James Shinra, Mor Elian, and Benjamin Damage.

Signing off on that notable era, the duo moves swiftly on with this limited 2 track white label of unadulterated festival-ready house epics that have been highlights of their sets over the past year.

Don’t Let Me glides along a chromatic world of lasered synths, pitched diva croons and shuffling pistons before a breathtaking swell of cinematic rave harmonics reaches a magnificent combustible peak that’ll have you gasping for Air.

The flip cracks the window open, dialling down the frenzy with a magnificent swooning melody sits on top of a growling Reese bassline and mechanized 2-step beat where a romantic ambience grows.

Limited stock. First come first served!

DJ Support:

Pete Tong Radio One Support 21.07.2023

Tim Sweeney supports 'Don't Let Me' on his Beats in Space podcast on Apple Music

John Digweed supports 'Air' on his recent Compiled and Mixed podcast for Apple Music

Jenny Greene 2FM Ireland supports 'Don't Let Me'

Long Island Sound Guest Mix on Jenny's 'The Greene Room' on 2fm Ireland

Tullio De Piscopo is an Italian drummer, percussionist and singer- songwriter born in Naples, Italy. During his musical career he began working as a session drummer, playing with international artists, including Chet Baker, Gil Evans, Gato Barbieri, Eumir Deodato and many others.

His 6th solo album Acqua E Viento, released in 1983, includes the Italian #1 single “Stop Bajon (Primavera)” which also ranked to #58 in the UK Singles Chart of that same year. “Stop Bajon (Primavera)” was a favourite in Rimini (Italy) Discotheques, a Balearic Islands classic, a Chicago favourite during the early house days, and became an anthem of the Italo Disco movement. The album includes guest musicians Don Cherry on trumpet, percussionst Famoudou Don Moye and composer and songwriter Pino Daniele.

Drummer and composer Tony Williams’ adventurous 1965 album Spring—his second as a leader for Blue Note—found him convening a stellar line-up with saxophonists Wayne Shorter and Sam Rivers, pianist Herbie Hancock, and bassist Gary Peacock. The five Williams originals presented here offer the musicians spacious realms in which to go exploring.

This Blue Note Classic Vinyl Edition is stereo, all-analog, mastered by Kevin Gray from the original master tapes, and pressed on 180g vinyl at Optimal.

Verwirrung - das Gefühl, perplex und verwirrt zu sein - ist die Inspiration für das neue Album von Pale Jay. Es ist eine gefühlvolle Erkundung des allmählichen Zerfalls einer Familie aufgrund von jahrelanger Vermeidung und Missverständnissen. Während dieser schwierigen Zeit begann Pale Jay, die Geschichten, mit denen er immer gelebt hatte, zu hinterfragen und seine Identität neu zu untersuchen. Das daraus resultierende Werk, Bewilderment, ist sein erstes komplettes Album, das Antworten auf diese und andere Fragen geben will. Pale Jay ist ein ausgebildeter Jazzsänger und Pianist und hat alle Songs des Albums geschrieben, aufgenommen und produziert, mit Ausnahme von "By The Lake", das in Zusammenarbeit mit seinen Labelkollegen Okonski - Steve Okonski, Aaron Frazer und Michael Montgomery - entstanden ist. Die Musik von Pale Jay ist von einer Vielzahl von Songwritern beeinflusst, darunter Labi Siffre, Carole King und William Onyeabor. Bewilderment ist eine nahtlose Mischung aus Pale Jays Markenzeichen, staubigem Soul, langsamer Disco- und Afrobeat, wobei die Streicherarrangements von Raven Bush den beatlastigen Produktionen eine zusätzliche Ebene der Magie verleihen. Pale Jays Debüt-LP ist eine fesselnde Reise der Selbstentdeckung. Jeder Song auf Bewilderment erzählt eine eigene Geschichte, aber alle haben ein gemeinsames Thema: persönliches Wachstum und Selbsterkenntnis.

Das dreifach RIAA-zertifizierte Platin-Debütalbum, gepresst auf 140g kristallklarem Vinyl, enthält die beiden Platin-Singles "Really Really" und "2 Phones".

Klar, bei der 9. Sinfonie von Antonín Dvořák geht die Post ab, auch in dieser Aufnahme. Aber das ist ja wohl nicht alles! Die Streicher von András Keller können blühen wie Blumen auf der Wiese. Sie spielen nicht gleichförmig, sondern in einer wie angeborenen Natürlichkeit, als wäre es eine Kleinigkeit, dass 14 erste Geigen so homogen klingen und gleichzeitig so individuell wie eine einzelne. Auch bei den Bläsern zählt nicht die Hochleistung oder der Zeigefinger ("Schaut her, so ist das gemeint"), sondern die Empfindsamkeit und das Strömen der Musik, z. B. im Englischhornsolo des langsamen Satzes. Das Blech: keine Kraftmeierei, sondern satte oder auch zarte, immer einfühlsame Akkorde. - Die Tempi, die Übergänge, alles fließt organisch und lädt zum Mitgehen ein. Das ist die hohe Kunst des Legato, die manchem als altmodisch galt, in Wirklichkeit aber zeitlos schön ist. Eins der Vorbilder von András Keller heißt, wen wunderts, Wilhelm Furtwängler. Genau in dieser Haltung, bar jeglichen Imponiergehabens entführt uns anschließend der von vielen geliebte Cellist Miklós Perényi behutsam in die geheimnisvolle Zauberwelt des Rondo op. 68/5 und der Waldesstille op. 95. Drei slawische Tänze aus op. 46 runden das Programm ab.

The fourth album from Australian metal masters, Parkway Drive. It was another creative leap forward for the chart-topping Australian band, "Atlas" boasts some of the most up front and confrontational material Parkway Drive has ever released, while at the same time taking several unexpected turns into lush sonic terrain, redefining their trademark sound while reinforcing their position as leaders in their field. the album includes the "Wild Eyes" which is a huge sing-a-long live anthem.

Back in 2003, during an incredible period of growth and reinvention for legendary artist MF DOOM, he introduced us to one of his numer- ous alter egos, Viktor Vaughn. As the story goes, Viktor Vaughn was an interdimensional time-traveling MC from an alternate realm where Hip-Hop was banned. He’d been exploring time and space looking for new dimensions to sharpen him to 90s era NYC, where he found himself stranded due to a mechanical mishap with his time machine. He began hitting open mics and small venues, battling other MCs and picking up a few side-hustles in order to raise enough funds to repair his time machine and get back to his travels.

Vaudeville Villain is a concept album like no other, where MF DOOM re-envisions himself as a younger, hungrier, more brazen persona, in order to explore subjects new and old from a different point of view. Of course, developing a second self from a more technologically advanced universe, he wanted to take a new approach to the produc- tion too. Viktor Vaughn fittingly raps over next-school beats that move freely in spaces between Electronica and Hip Hop, all courtesy of Sound-Ink producers King Honey, Heat Sensor and Max Bill, with the exception of one track produced by RJD2. Featuring all original lyrics by DOOM, with a few notable guest appearances from M. Sayyid (Anti-Pop Consortium), Lord Sear, Apani B Fly MC, Louis Logic, and more, Vaudeville Villain is one of the more uniquely creative entries in the MF DOOM universe.

Undeniably one to watch, the release of his upcoming body of work is set to cement Sam’s status as one of the year’s most exciting new artists. His music has already been praised by the likes of MTV, Clash, BBC, and Notion magazine, played across BBC Radio 1 by Scott Mills, Clara Amfo, Ricky, Melvin and Charlie, and featured on flagship Spotify editorial playlists. Elton John and Bastille are fans, pop phenomenon Bebe Rexha has co-signed his work, while Justin Bieber is a prominent supporter. The two hosted a sensational IG Live together and more recently hung out in LA, while a video of Justin singing Sam’s single ‘Whole’ has gained more than one million views –and counting. Closer to home, JayKae jumped onstage on Sam’s last tour, and renowned UK tag-team Krept & Konan are fans. Such a broad spread of support simply represents his audience as a whole; there’s a literal army of TikTok followers moving alongside him, with Sam amassing almost a half million followers on Instagram –that’s more than some very established artists. In fact, he already has more Instagram followers than some winners at the BRITs last year. Matching pop touches to a classic feel, he’s often compared to Sam Fender’s anthemic truth-seeking or Tom Walker’s revelatory autobiography. Yet Sam’s work stands alone and is already scaling

The hotly anticipated follow-up to 2007"s Horizons, Deep Blue raised the bar in every conceivable way. While maintaining the band"s uncompromising metallic-hardcore style at its core, it pushes into exciting new realms, drawing from a wider scope of influence, incorporating everything from anthemic pop-punk to bloodcurdling death metal. Including classic songs such as "Karma" and "Sleepwalker".

Saxophonist Charles Lloyd ist musikalischer Freigeist und Jazz-Visionär, seit mehr als sechs Jahrzehnten
Unikum der internationalen Szene und mit 84 Jahren noch immer im Vollbesitz seiner kreativen Kräfte.
Mit „Trios: Chapel“ eröffnete Lloyd im Juli 2022 ein ungewöhnliches Trio-Projekt, das insgesamt drei
thematisch zusammenhängende Alben umfasst, die ihn jeweils in einer anderen Trio-Besetzung präsentieren - ein „Trio of Trios“. Das erste Album nahm er mit Gitarrist Bill Frisell und Bassist Thomas Morgan
auf, das jetzt erscheinende zweite, ”Trios: Ocean” mit Gitarrist Anthony Wilson und Pianist Gerald Clayton, und das dritte, „Trios: Sacred Thread“ (erscheint am 18. November), mit Gitarrist Julian Lage und
Schlagzeuger Zakir Hussain.

Die gemeinsamen Alben und Auftritte des legendären Filmkomponisten John Williams und der Stargeigerin Anne-Sophie Mutter gehören zweifellos zu den Highlights der letzten Jahre. Dieses Album ist das neueste Ergebnis der langjährigen Freundschaft und Zusammenarbeit der weltweit gefeierten Künstler: Mutter spielt das Zweite Violinkonzert von John Williams, das der Komponist für sie geschrieben hat. Williams sagt über sein Violinkonzert: „Für mich geht es in diesem Stück vor allem um Anne-Sophie Mutter und
um die Violine als Meisterwerk der Geigenbaukunst. (…) letztlich wurde diese große Künstlerin selbst zu meiner Inspiration und Antriebskraft.“ Die vorliegende Aufnahme für die Deutsche Grammophon, mit dem Boston Symphony Orchestra unter der Leitung von Williams selbst, entstand kurz nach der Uraufführung
des Zweiten Violinkonzertes im Juli 2021 in Tanglewood. Der Boston Globe schrieb: „Selbst in dieser Uraufführung trug Mutter das Solo wie eine alte Freundin und formte jede Phrase mit Absicht und Elan.“
Dem lyrischen und sehr persönlichen Konzert folgen auf dem Album drei fantastische Zugaben: Beliebte Filmthemen von Williams, u.a. aus Star Wars und Indiana Jones, die er alle komplett neu für Anne-Sophie
Mutter arrangiert hat. In diversen Details des Violinkonzertes, aber auch in den schönen Filmmelodien, spiegelt sich die Ausdruckskraft von Mutters Spiel ebenso wie ihre virtuose Brillanz und die lyrische Wärme ihres Geigentons.

After decades of near silence, the old skool scene was shocked and thrilled to hear about a new Acen release, and here it is on vinyl! An absolutely amazing slice of old skool that also looks to the future in a classic Acen style, this one is sure to fly! All three tracks on the EP are authentic and incredible and deserve pride of place in any collectors collection!

Club / DJ Support
Billy Bunter, the Fat Controller, Glowkid, Slipmatt, Dj Jedi, Dj Luna-C, Dj Brisk, Clayfighter, Jimni Cricket, Bustin, Sc@r, Doughboy, Saiyan, Dave Skywalker, Liquid, Hyper On Experience, Ant To Be, Ponder and many others